All functions

GeneInfo()

Get Genomic Information

MGH136

Glioblastoma patient MGH136

Markers_Normal

Marker gene sets of Normal Cell Types and Pan-Cancer Programs

NormalBrainSignatures2

98 Signatures for Normal Brain Cell Types

NormalBrainSignatures3

178 Signatures for Normal Brain Cell Types

NormalSignatures

205 Signatures for Normal Cell Types

Sapply()

sapply wrapper

Unlist()

Unlist, keeping original list or element names

add_to_dataframe()

Join a dataframe and a named vector

aggr_gene_expr()

log-Average expression of genes across all cells

alias2ensembl()

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alias2entrez()

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alias2refseq()

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alias2symbol()

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alias2ucsc()

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allowedExons()

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annomap()

One-bar annotation ggplot

as_bulk()

Convert sc-matrix to simulated bulk

as_bulk_samples()

Convert sc-matrix to simulated bulk samples matrix

as_four_state_gbm()

Convert 6-state to 4-state GBM scores

assign_bulk_states()

Assign Samples to States by High- and Low -frequency of their Cells in each State

baseScores()

Basic Scoring of Matrix by Gene sigs

bin()

Generate Equally-Sized Bins

binmatch()

Control Signatures From Expression Bins

bootstrap_summary()

Summary Statistics for Bootstrapped State Fractions

bootstrapped_state_fractions()

Bootstrapped State Fractions

cluster.methods

agglomeration method in hierarchical clustering agglomeration method in hierarchical clustering when grouping members into a tree structure.

col_subset()

Keep columns whose names match a pattern

colcenter()

Center a matrix column-wise

coldetected()

Number of non-zero values per column

combine_group2_dea()

Aggregate `scalop::dea` output for one group against many in turn

comply()

Apply a Function to All Pairs of Elements in 'x' or Between 'x' and 'y'

cor.methods

Correlation method method for computing correlation coefficients

cpm()

Convert Counts to Counts-Per-Million (CPM)

dea()

Differential Expression Analysis

dims()

<dim> for many matrices

discrete_colours

The 297 discrete colours available across different RColorBrewer palettes.

dist.methods

distance metric method for computing distances from a matrix object

doubletCells()

Identify potential doublet cells

enricher()

Functional enrichments

`=`()

ensembl2symbol

entrez2alias()

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entrez2ensembl()

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entrez2refseq()

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entrez2symbol()

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entrez2ucsc()

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expr_housekeeping()

Expression level of Housekeeping Genes

filter_signatures()

Filter Out Lowly-Correlated Genes from Signature(s)

filter_sigs()

Filter genes in sigs according to reference

fitBimodal()

Fit a Bimodal Gaussian Distribution

flip()

Flip the (nested) elements of a character vector (or list) with its names

foldchange()

fold changes

frac_mito()

Fraction of a Cell's Expression Level Coming From Mitochondrial Genes

futurama

futurama, 12 Discrete Colours

geneLength()

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genericModel()

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getGRCh()

Get hg19 or hg38 information from biomaRt

get_ensembl()

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get_entrez()

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get_genes()

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get_refseq()

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get_signatures()

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get_snn_graph_clusters()

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get_symbols()

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get_ucsc()

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ggDensity()

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ggmap()

gmap wrapper

ggoutliers()

Plot model and Outliers

ggpubr

ggpubr, 3 Discrete Colours

ggvolcano()

Volcano plot

gmap()

Plot A Heatmap with ggplot2

graster()

Plot A Heatmap with ggplot2

grombine()

Combine ggplot grobs or plots

grouped_reorder()

Grouped Reorder and Ungroup

grouped_rowcenter()

Center matrix rows by subsets of columns

hca() hca_cor() hca_dist() hca_tree() hca_order() hca_groups() hca_reorder()

Hierarchical clustering analysis

headl()

Left-hand head a matrix or dataframe

headr()

Right-hand head a matrix or dataframe

hierarchy()

Cell state hierarchy coordinates

hms_span()

Subtract POSIXt Class Objects in HH:MM:SS Format

is_accnum()

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is_alias()

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is_annotation()

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is_ensembl()

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is_entrez()

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is_refseq()

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is_symbol()

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is_ucsc()

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jacFilt()

Filter List By Jaccard

Jaccard()

Compute Jaccard Similarities between Pairs of Character Vectors

jacmap()

Convert a list to a jaccard matrix and plot with `scalop::gmap`

ldcast()

Turn a list into a dataframe

logRowMeans()

Row Means of Log2 data

logcpm()

Convert CPM to logCPM

map_alias()

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map_ensembl()

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map_entrez()

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map_genes()

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map_refseq()

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map_symbol()

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markerScores()

Score a Matrix with Marker Gene Sets Of Normal Cell Types

mat01()

Character List to Binary (membership) Matrix

maxcol_strict()

Strict Column Assign

metaprograms()

Compute Metaprograms

msigdb()

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nSigGenes()

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ncols()

<ncol> for many matrices

nrows()

<nrow> for many matrices

ntop()

Select top n elements

ohmySNNclusters()

SNN Graph-Based Clustering

ohmyqc()

Quality control statistics for single cell RNA seq data

ohmytsne()

A plot-friendly output for the Barnes-Hut implementation of t-SNE.

outliers()

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Overlap()

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pairup()

List combinations

pal19

pal19, 19 Pretty Discrete Colours

pal28

pal28, 28 Pretty Discrete Colours

palG34R

palG34R, a palette of reds and blues for cases within two groups

pca()

Principal Component Analysis

plot_hierarchy()

Plot State Hierarchy (Quadrant plot)

programs()

Find cell clusters and retrieve significant expresion programs

range_rowmeans()

Range of the rowMeans of a matrix

refseq2alias()

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refseq2ensembl()

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refseq2entrez()

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refseq2symbol()

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refseq2ucsc()

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row_subset()

Keep rows whose names match a pattern

rowcenter()

Center a matrix row-wise

rowdetected()

Number of non-zero values per row

sample_strict()

Assign Rows and Sample

scdata

scRNA-seq data from a patient with Glioblastoma

score()

Score matrix columns for groups of rows

setColNames()

Set the colnames in an object

setRowNames()

Set the rownames in an object

sigScores()

Score a Matrix by Gene sigs (Signatures)

simpsons

simpsons, 16 Discrete Colours

state_fractions()

State Fractions (by group)

state_high_genes()

Genes Associated with High Frequency of a Cellular State

subsplit()

Split a vector, list, matrix or dataframe into into a list of matrices or nested list according to substring matches.

substri()

Extract substrings between delimiters by position

symbol2alias()

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symbol2ensembl()

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symbol2entrez()

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symbol2refseq()

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symbol2ucsc()

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taill()

Left-hand tail a matrix or dataframe

tailr()

Right-hand tail a matrix or dataframe

theme_scalop()

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totalExons()

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tpm()

Convert logTPM to TPM

ucsc2alias()

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ucsc2ensembl()

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ucsc2entrez()

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ucsc2refseq()

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ucsc2symbol()

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unique_sample_names()

Get unique sample names

unlogcpm()

Convert logCPM to CPM

logtpm() unlogtpm()

Convert TPM to logTPM

vannomap()

One-bar annotation ggplot

which_annotation()

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wilcoxtest()

wilcoxon-tests

x2y()

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